RESEARCH PUBLICATIONS

  Publications:

1. S. Maharjan, B. Mopidevi, M.K. Kaw, N. Puri and A. Kumar. Human Aldosterone synthase gene polymorphism promotes miRNA binding and regulates gene expression. Physiological Genomics 2014 Dec; 46 (24) 860-865.
2. L. Serova, S. Maharjan, R. Nostramo and E. Sabban. Estradiol-mediated regulation of gene expression of catecholamine biosynthetic enzymes: The role of membrane-initiated signaling with ERa. Book Chapter. Catecholamine Research in the 21st Century 2013, 10th International Catecholamine Symposium, Academic Press, USA.
3. R. Nostramo, A. Tillinger, A. Kumar, J. Saavedra, V. Pandey, L.I. Serova, S. Jain, S. Maharjan and E.L. Sabban. The broadened renin-angiotensin system of the adrenal medualla: Stress triggered changes in gene expression. 2012 (submitted).
4. S. Maharjan, B. Mopidevi, V.G. Pandey, S. Jain and A. Kumar. The role of microRNAs in the regulation of human aldosterone synthase gene expression. Hypertension 2012; 60 (3): A101
5. B. Mopidevi, S. Maharjan, S. Jain,V.G. Pandey and A. Kumar. MicroRNAs hsa-miR-584 and hsa-miR-31 regulate expression of human angiotensinogen gene. Hypertension 2012; 60 (3): A239
6. S. Jain, A. Prater, V. Pandey, S. Arudra, B. Mopidevi, S. Maharjan, and A. Kumar. Differential Regulation of blood pressure in transgenic mice containing two haplotypes of human angiotensin receptor type 1. Hypertension 2012; 60 (3): A626,
7. V.G. Pandey, S. Jain, S. Maharjan, B. Mopidevi, S.K.C. Arudra and A. Kumar. Dexamethasone differentially regulates blood pressure in transgenic mice containing -217A/G polymorphism of human angiotensinogen gene. FASEB J March 29, 2012 (26):874.18
8. S. Jain, V.G. Pandey, S. Maharjan, B. Mopidevi, S.K.C. Arudra and A. Kumar. Differential Regulation of blood pressure in transgenic mice containing -217A/G polymorphism of human angiotensinogen gene in response to immobilization stress. FASEB J March 29, 2012 (26):1098.10
9. E.L. Sabban, A. Tillinger, R. Nostramo. A. Kumar, V. Pandey, L. Serova and S. Maharjan. Stress triggered modulation of renin angiotensin system in adrenal medulla: Implications for catecholamine biosynthesis. Society of Neuroscience 2011, Washington Convention Center, DC, USA.
10. V. Pandey, B. Mopidevi, S. Jain, S. Maharjan, S.K.C. Arudra and A. Kumar. Transgenic mice with -217A haplotype of the human angiotensinogen gene have significantly increased expression of hAGT in kidney as compared to -217G haplotype. Hypertension 2011; 58 (5): e85.
11. S. Maharjan, B. Mopidevi, V.G. Pandey, S. Jain and A. Kumar. The haplotype containing -663T, -470T and -344C of hCYP11B2 gene has increased transcriptional activity compared to -663A, -470C and -344T. Hypertension 2011; 58 (5): e100.
12. S. Jain, V.G. Pandey, A. Tillinger, S. Maharjan, E.L. Sabban and A. Kumar. Immobilization stress response and the modulation of rennin angiotensin system. Hypertension 2010; 56 (5): e51.
13. S. Maharjan, L.I. Serova and E.L. Sabban. Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells. J Neurochem. 2010 Jan; 112 (1) 42-55
14. E.L. Sabban. S. Maharjan, R. Nostramo and L.I. Serova. Divergent effects of estradiol on gene expression of catecholamine biosynthetic enzymes. J Physiol Behav. 2010 Feb; 99 (2) 163-8.
15. L.I. Serova, H.A. Harris, S. Maharjan and E.L. Sabban. Modulation of response to stress by estradiol benzoate and selective estrogen receptor agonists. J Endocrinol. 2010 Jun; 205 (3) 253-62.
16. S. Maharjan. Mechanism of estrogen triggered regulation of tyrosine hydroxylase gene transcription. Book. 2009 Biochemistry and Molecular Biology, Graduate School of Basic Medical Sciences, New York Medical College, New York, USA.
17. S. Maharjan, L.I. Serova and E.L. Sabban. Mechanisms for differential effects of estrogen on tyrosine hydroxylase (TH) gene transcription. FASEB J April 22, 2009 (23): 941.14
18. L.I. Serova, R. Nostramo, S. Maharjan and E.L. Sabban. Interaction between nicotine and estradiol in regulation of gene expression in substantia nigra (SN) in animal model of Parkinson’s disease (PD). FASEB J. April 22, 2009 (23): 963.5
19. S. Maharjan, L.I. Serova and E.L. Sabban. Membrane initiated estrogen signaling regulates tyrosine hydroxylase promoter activity with ERα in PC12 cells. Society of Neuroscience 2008, Washington Convention Center, DC, USA.
20. L.I. Serova, S. Maharjan, M. Veerasirikul and E.L. Sabban. Estrogen regulates GTP cyclohydrolase I gene expression: Role of estrogen receptors subtypes and interaction with cAMP. University of Albany 2008, State University of New York, NY, USA.
21. S. Maharjan, L.I. Serova and E.L. Sabban. Involvement of CREB in the regulation of tyrosine hydroxylase gene transcription by estrogen and modulation of response to cAMP. Society of Neuroscience 2007, San Diego Convention Center, CA, USA.
22. E.L. Sabban, L.I. Serova, S. Maharjan, D. Glazkova, M. Veerasirikul and N. Schilt. Effects of estrogens with ERα or ERβ on transcriptional regulation of catecholamine biosynthetic enzymes. FASEB J October 28, 2006 20:A258
23. E.L. Sabban, L.I. Serova, S. Maharjan, D. Glazkova, M. Veerasirikul and N. Schilt. Transcriptional regulation of catecholamine biosynthetic enzymes by estrogen: role of ERα or ERβ and interaction with cAMP. The Endocrine Society’s 88th Meeting 2006. Boston, MA, USA.
24. S. Maharjan. Transcriptional regulation of tyrosine hydroxylase by estrogen: opposite effects with ERalpha and ERbeta and interactions with cAMP. Book. 2005 Biochemistry and Molecular Biology, Graduate School of Basic Medical Sciences, New York Medical College, New York, USA.
25. S. Maharjan, L.I. Serova and E.L. Sabban. Transcriptional regulation of tyrosine hydroxylase gene by estrogen: Opposite effects with estrogen receptors alpha and beta and interactions with cyclic AMP. J Neurochem. 2005 Jun; 93 (6) 1502-14.
26. L.I. Serova, S. Maharjan and E.L. Sabban. Estrogen modifies stress response of catecholamine biosynthetic enzyme genes and cardiovascular system in ovarectomized female rats. Neuroscience. 2005; 132 (2): 249-59.
27. L.I. Serova, S. Maharjan, A. Huang, D. Sun, G. Kaley and E.L. Sabban. Response of tyrosine hydroxylase and GTP cyclohydrolase I gene expression to estrogen in brain catecholaminergic regions varies with mode of administration. Brain Res. 2004 Jul 23; 1015 (1-2): 1-8.
28. S. Maharjan, L.I. Serova and E.L. Sabban. Response of catecholamine biosynthetic enzyme gene expression to estrogen in brain varies with dose and mode of administration. Society of Neuroscience 2004, San Diego Convention Center, CA, USA.
29. S. Maharjan, L.I. Serova and E.L. Sabban. Estradiol alters tyrosine hydroxylase transcription: opposite effects with ERα and ERβ and interactions with cAMP. Society of Neuroscience 2004, San Diego Convention Center, CA, USA.
30. L.I. Serova, S. Maharjan, L. Kolesnikova and E.L. Sabban. Estrogen modifies stress response of catecholamine biosynthetic enzyme genes and cardiovascular system in ovariectomized female rats. Society of Neuroscience 2003, Washington Convention Center, DC.
31. S. Maharjan. The mechanism of sulfite formation in rabbit polymophonuclear leukocytes and small intestinal mucosa. Book. 1996. Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
32. S. Maharjan. The process of sulfation of biological molecules with particular reference to the different purposes that living organisms achieve by the sulfation reactions. Literature Review. 1995. Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
33. H.C. Robinson, S. Maharjan, C.J. Handley and Z. Yang. An assay for 3'-phophoadenosine 5'-phosphosulphate-reductase. (Under publication)
34. S. Maharjan. Regulation of recombination, DNA repair and competence for genetic transformation in Bacillus subtilis. Essays. 1994. Molecular Microbiology and Diagnostic Immunology, Monash University, Melbourne, Australia.
35. S. Maharjan. Genes involved in the regulation of Apoptosis - a programmed cell death. Essays. 1994. Biochemistry and Molecular Biology, Monash University, Melbourne, Australia.
36. S. Maharjan. The availability of genomic length cDNA for a positive strand RNA virus (e.g. Flaviviruses: Yellow fever, Japanese encephalitis, Tick-borne encephalitis, Dengue and Kunjin viruses) allows significant opportunities for the study of viral replication and pathogenesis. Essays. 1994. Molecular Microbiology and Diagnostic Immunology, Monash University, Melbourne, Australia.