LIPOPROTEIN METABOLISM

Transport of Fat to Tissues: Lipoproteins Chylomicrons constitute just one class oflipoproteins found in the bloodstream. These complexes play essential roles in the transport oflipids to tissues,either for energy storage or for oxidation.Free lipids are all but undetectable in blood. The polypeptide components oflipoproteins are called apoproteinsor apolipoproteins. These are synthesized mainly in the liver,though about 20% are produced in...

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Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

Abstract The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The development of multifunctional and stimulus-sensitive NDDSs is an active area of current research. Such NDDSs can have long circulation times, target the site of the disease and enhance the intracellular delivery of a drug. This type of NDDS can also respond to local stimuli that are characteristic...

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