The Nutshell: Tumor Exosomes Make microRNAs

Tumor Exosomes Make microRNAs Cellular blebs shed by tumor cells can process short stretches of RNA that go on to induce tumor formation in neighboring cells. By Kerry Grens | October 27, 2014   WIKIMEDIA, NATIONAL CANCER INSTITUTE Cells give off little membrane-bound bubbles called exosomes, which are known to contain microRNAs (miRNAs)—short stretches of RNA that can interfere with protein production. Exosomes have also been...

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Immune cells in experimental acute kidney injury

Nature Reviews Nephrology:   The immune system has a vital role in the renal response to acute kidney injury (AKI). In this Review, Hye Ryoun Jang and Hamid Rabb describe current understanding of the function of the innate and adaptive immune systems in the early and late injury phases of ischaemic and nephrotoxic AKI, and describe the influence of immune cells on recovery and long-term outcome following AKI.    Abstract:   Acute...

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Male infertility: a public health issue caused by sexually transmitted pathogens

Nature Reviews Urology:   Sexually transmitted diseases caused by bacteria, viruses and protozoa can affect the male genital tract. Gimenes and colleagues discuss the evidence for effects of sexually transmitted pathogens on semen, sperm and male infertility.   Fabrícia Gimenes,1, Raquel P. Souza,1, Jaqueline C. Bento,3, Jorge J. V. Teixeira,2, Silvya S. Maria-Engler,4, Marcelo G. Bonini5, & Marcia E. L. Consolaro1,   Published...

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